Multiple clear cell acanthoma in a patient with psoriasis. Treatment with 5-fluorouracil
García Almagro, D.; Bueno, C.; Corripio, F.; Lecona, M.; Jaqueti, G.
Medicina Cutanea Ibero-Latino-Americana 7(4-6): 109-113
1979
ISSN/ISBN: 0210-5187 PMID: 399310 Document Number: 150335
Clear cell acanthoma (CCA) is a benign skin tumour, seldom multiple, perfectly individualized both clinically and histologically. The tumour is more usually mistaken for a seborrheic keratosis. There are large amounts of glycogen within the epidermal cells as can see upon staining with the PAS reaction. Melanogenesis is decreased. The enzymes characteristic of eccrine sweat glands are also decreased. The authors report a 67 years old psoriatic female with 15 C.C.A. They emphasize the treatment with topic 5FU particularly interesting in the multiple forms.