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Characteristics of the effect of estradiol on prolactin secretion by adenohyophyseal cells from intact and ovariectomized rats in primary monolayer cultures

Peres Arse, K.A.; Komolov, I.S.; Fedotov, V.P.

Biulleten' Eksperimental'noi Biologii i Meditsiny 88(7): 92-94

1979

ISSN/ISBN: 0365-9615
PMID: 223691
Document Number: 149381
Estradiol directly stimulated the secretion of prolactin by the adenohypophyseal cells of intact rats in a monolayer culture. Complex interactions between estradiol and some other regulators of the hypophyseal lactotropic function were revealed. It was established that changes in prolactin synthesis and secretion in ovariectomized rats persisted for 3--4 days of adenohypophyseal cell cultivation in vitro.

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