Severe reaction to 5% imiquimod cream with excellent clinical and cosmetic outcomes
Greenberg, H.L.; Cohen, J.L.; Rosen, T.; Orengo, I.
Journal of Drugs in Dermatology Jdd 6(4): 452-458
2007
ISSN/ISBN: 1545-9616 PMID: 17668546 Document Number: 14892
Imiquimod, an immune response modifier approved for the treatment of external genital warts, actinic keratoses, and superficial basal cell carcinoma, can induce a severe local inflammatory response. This phenomenon can accompany inappropriately overzealous, as well as entirely conventional, drug utilization. Despite strikingly brisk reactions, the 9 patients reported herein ultimately experienced excellent cosmetic and clinical outcomes. We report this series to alert clinicians of the good prognosis for a satisfactory outcome even when faced with extreme imiquimod cream-induced inflammation.
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