Prothrombin time standardization report of the expert panel on oral anticoagulant control: a minority opinion
Miale, J.B.
Thrombosis and Haemostasis 42(4): 1132-1134
1979
ISSN/ISBN: 0340-6245 PMID: 542926 Document Number: 148608
The ICTH/ICSH collaborative study failed to achieve its aims because each combination of plasma, thromboplastin and method was tested by too few laboratories in relation to intra and inter laboratory variation, and because the stability of the reference thromboplastin 70/178 is suspect. The evidence of the study does not support the superiority of reference thromboplastins over reference plasmas, but the concept of reference plasma was not adequately explored.
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