Increased work of breathing associated with nasal prongs
Goldman, S.L.; Brady, J.P.; Dumpit, F.M.
Pediatrics 64(2): 160-164
1979
ISSN/ISBN: 0031-4005 PMID: 38429 Document Number: 148569
To determine if continuous distending pressure (CDP) given by nasal prongs increases work of breathing, the mechanics of breathing, minute ventilation and blood bases were measured in 9 infants with both nasal prong and face mask CDP. Minute ventilation was 16% larger (P < .02), work of breathing was 94% higher (P < .01) and the mean PaO2 [arterial O2 pressure] was 8 mm Hg lower (P < .03) with the nasal prongs. There was no difference in pH or PaCO2 [arterial CO2 pressure]. CDP given by nasal prongs may increase the risk of respiratory failure in the premature infant already compromised with hyaline membrane disease.