Chromosome heteromorphism in children with congenital malformation
Ghosh, P.K.
Indian Journal of Experimental Biology 17(11): 1186-1189
1979
ISSN/ISBN: 0019-5189 PMID: 549843 Document Number: 147999
The frequency of chromosome heteromorphism as detected by conventional, G-banding methods were examined among children with congenital malformations (n = 50) and normal children (n = 50) serving as control. A significant difference in the distribution of minor chromosome variants was found among the 2 groups. C-band heteromorphism was more common in children with congenital malformations than in controls, especially for the inversion of chromosome 9. Minor chromosomal variants may effect development in humans.