Action of metoclopramide bromide and metoclopramide chloride on the lower esophagogastric junction and the peristalsis of the lower 3d of the esophagus
Lazaroni, F.A.; Chiocca, J.C.; Salis, G.B.; Mazure, P.A.
Acta Gastroenterologica Latinoamericana 9(1): 15-22
1979
ISSN/ISBN: 0300-9033 PMID: 494997 Document Number: 147985
In 10 patients with esophageal hiatus hernia the effect of metoclopramide bromide and metoclopramide chloride compared with placebo, was studied by the double blind method. Both drugs produced an increase of the lower esophageal sphincter pressure and of the peristalsis of the lower third of the esophagus, only being statistically significative the action of metoclopramide chloride on the perstalsis. No significative side-effects were noted.