Relevance of complementary methods to examine patients with intra-uterine pathological phenomena
Saveljeva, G.M.; Breusenko, V.G.
Zentralblatt für Gynakologie 101(15): 976-980
1979
ISSN/ISBN: 0044-4197 PMID: 532424 Document Number: 146457
785 women underwent the following tests to diagnose pathological intrauterine developments: hysteroscopy, radioisotopic examination of the endometrium, determination of nucleic acid levels, measurement of endometrial mitosis, the karyopycnotic index, and radioimmunological determination of serum hormone levels. In cases of endometrial cancer, an average level of P32 of 322.2% +/- 129.3% was found. Hyperplastic processes also caused an elevated P32 count, average 214% +/- 57.95%; in 9 of the 179 cases of hyperplasia, these values approached those for endometrial cancer. The RNS content is about 1.5 times greater than normal in the case of endometrial cancer, on the average 2.25 +/- .9; in cases of hyperplasia the average was 1.55. RNS was found to be 2.0-2.9 in cases of recurring hyperplasia or polyp formation. The measurement of cell mitosis was the most irregular in cases of endometrial adenocarcinoma. All patients with endometrial complaints should be examined carefully to determine the possible presence of endometrial cancer.