High-dose methotrexate in malignant melanoma
Karakousis, C.P.; Carlson, M.
Cancer Treatment Reports 63(8): 1405-1407
1979
ISSN/ISBN: 0361-5960 PMID: 314335 Document Number: 146447
High-dose methotrexate was given to 28 patients with advanced malignant melanoma who had previously failed to respond to two chemotherapy protocols. There were five instances of serious, but not fatal, toxicity. One patient has had an objective response and seven patients have had stabilization of disease with an average duration of 4 months.
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