Computer-assisted morphometric analysis for three-dimensional cell shape
Simone, J.N.; Welling, L.W.; Welling, D.J.
Laboratory Investigation; a Journal of Technical Methods and Pathology 41(4): 334-339
1979
ISSN/ISBN: 0023-6837 PMID: 385977 Document Number: 146398
Quantitative, morphometric analysis of 3-dimensional cell shape may prove to be a valuable adjunct to scanning electron microscopy and to the evaluation of epithelial transport phenomena. Therefore, to facilitate the wider use of cell shape analysis, a computer-assisted technique has been developed to supplement or replace the usually tedious and otherwise limited manual techniques previously available. The computer programs described here have been designed to run in a small laboratory computer, do not require a large amount of operator time, and are shown to provide an accuracy and efficiency not practical with manual procedures.