Derivation of a velocity equation for a reaction model witwh two binding sites for acetylcholinesterase
Principato, G.B.; Giovannini, E.; Mallone, L.; Menghini, A.R.
Bollettino della Societa Italiana di Biologia Sperimentale 55(8): 757-761
1979
ISSN/ISBN: 0037-8771 PMID: 554645 Document Number: 146092
The authors suggest a kinetic model with two binding sites for acetylcholinesterase; it is suitable to study particular enzyme forms that show a kinetic pattern which cannot be explained by the model with a single binding site of Krupka and Laidler. The velocity equation was obtained using the algorithm of King and Altman and carrying out elementary calculations.