Some problems in the bioassay of haematological drugs
Thomas, D.P.
Developments in Biological Standardization 44: 179-183
1979
ISSN/ISBN: 0301-5149 PMID: 120812 Document Number: 144144
The principles of biological standardization are well understood and generally accepted. However, discrepancies in potency estimates due to inter-method and inter-laboratory variations in assay hinder general agreement on potency values for certain biological drugs used in treating disorders of haemostatis. While attempts are made to minimize these differences, the magnitude of existing inter-laboratory discrepancies should be acknowledged.