Corticosteroid-sensitive chemical diabetes in Horton's disease
Christmann, D.; Pasquali, J.L.; Meyer, F.; Lutun, P.; Meyer, R.; Warter, J.; Storck, D.
La Nouvelle Presse Medicale 8(34): 2735-2738
1979
ISSN/ISBN: 0301-1518 PMID: 493079 Document Number: 143616
We report 5 cases of temporal arteritis associated with a diabetes whose good evolution under corticotherapy suggests a common pathogenesis. Several hypotheses can be formulated to explain the origin of the glycemic abnormality and to understand the way corticotherapy is effective. A moderate posology could at first have a hyperplasic effect on the insulin-secreting cells, and later on a favorable action on the vascular lesion and on an immunological disorder. Any definitive conclusion cannot be evolved yet. Only a more systematical study of the glycoregulation's abnormalities in the temporal arteritis will enable to answer the many remaining questions.