Monocyte cytotoxicity in Hodgkin's disease
Pehamberger, H.; Ludwig, H.; Pötzi, P.; Pietschmann, H.; Knapp, W.
Acta Medica Austriaca 6(5): 249-251
1979
ISSN/ISBN: 0303-8173 PMID: 555222 Document Number: 143124
Monocyte mediated antibody dependent cellular cytotoxicity (ADCC) was determined in 23 patients with Hodgkin's disease and 29 normal healthy controls. ADCC activity of monocytes was found to be significantly increased (p less than 0.01) in patients when compared to the controls. No significant difference was observed in the number of non specific esterase positive-monocytes in both groups of individuals, investigated. Thus increased ADCC activity of monocytes in Hodgkin's disease in this particular ADCC system is due to an increased lytic capacity of monocytes.