Prevalence of low birthweight infants in HIV-infected women delivered in Rajavithi Hospital
Asavapiriyanont, S.; Kasiwat, S.
Journal of the Medical Association of Thailand 94(Suppl 2): S66-S70
2011
ISSN/ISBN: 0125-2208 PMID: 21717881 Document Number: 14296
To determine the prevalence of low birthweight infants in HIV-infected pregnant women delivered in Rajavithi Hospital and the relationship between antiretroviral drugs and low birthweight infants. All numbers of low birthweight (LBW) infants and pregnant women with or without HIV infection delivered in Rajavithi Hospital during 2004-2008 from medical records were used. Two hundred HIV-infected pregnant women who delivered their infants at the same period were random for description and analysis. The prevalence of low birthweight infants delivered by HIV and non HIV-infected pregnant women were 12.6% (53/ 420) and 13.3% (4,249/31,975), respectively. There was no significant association between HIV infection and low birthweight (p = 0.688). Low birthweight infants delivered from HIV-infected pregnant women with and without antiretroviral therapy were 9.9% (7/41) and 13.6% (19/159), respectively. Various types of antiretroviral (ARV) drug including no ARV were significantly associated with LBW (p = 0.021). The one who received highly active antiretroviral therapy (HAART) had 2.27 times higher risk in having LBW. The prevalence of low birthweight infants among HIV-infected pregnant women was 12.6%. There was no association between HIV infection and LBW. HAART might be a risk of LBW.