Rat thrombocyte factor XIIi and its role in platelet aggregation
Pastorova, V.E.; Umarova, B.A.; Sukhanova, S.A.
Biulleten' Eksperimental'noi Biologii i Meditsiny 87(2): 99-101
1979
ISSN/ISBN: 0365-9615 PMID: 420942 Document Number: 139326
Factor XIII was isolated from rat platelets; it activity was 1430 units per 1 mg of protein. It was shown in experiments in vitro that addition of this factor (160--200 units/ml) to the suspension of washed platelets or those purified by passage through the column with sepharose 4B increased their aggregation capacity. Addition of inactive platelet factor XIII failed to influence the platelet aggregation induced by ADP.
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