Blood bupivacaine levels in standard and segmental epidural blockade in obstetrics
Du T Zaaijman, J.; Slabber, C.F.
South African Medical Journal 55(23): 913-914
1979
ISSN/ISBN: 0256-9574 PMID: 472928 Document Number: 139175
A statistically significant reduction in maternal blood bupivacaine levels could be achieved by using a segmental epidural blockade and lower concentrations of bupivacaine. Since bupivacaine has certain potential disadvantages for the mother and the fetus, its dosage should be kept as low as possible. Significantly lower blood levels without loss of analgesic quality are obtainable by using segmental epidural blockade and a lower concentration of bupivacaine.