Outcomes of complete radical hysterectomy in early-stage cervical cancer patients with intra-operative detection of nodal metastases
Tuipae, S.; Wongsuwan, C.
Journal of the Medical Association of Thailand 96(Suppl 3): S35-S41
2013
ISSN/ISBN: 0125-2208 PMID: 23682520 Document Number: 13899
To determine the overall 5-year survival rate and treatment-related complications in stage IB-IIA cervical cancer patients with intra-operative detection of pelvic node metastases who underwent complete radical hysterectomy and systematic lymphadenectomy. The medical records of FIGO stage IB-IIA cervical cancer patients who underwent radical hysterectomy and pelvic lymphadenectomy in Rajavithi Hospital between January 1985 and December 2006 were retrospectively reviewed. Of the 247 node-positive stage IB-IIA cervical cancer patients, 121 patients displayed evidence of intra-operative detection and underwent complete radical hysterectomy with systematic lymphadenectomy. These 121 patients were reviewed of which 107 were in stage IB and 14 were in stage IIA. Overall 5-year survival rate and treatment-related complications were investigated. The median follow-up period was 117 months (range 60-312 months). Of the 121 stage IB-IIA cervical cancer with intra-operative detection of pelvic node metastases who underwent complete radical hysterectomy and pelvic lymphadenectomy, the overall 5-year survival rate was 70.5%. The major treatment-related complications were intraoperative hemorrhage and post-operative bladder atony which accounted for 43.0% and 10.7%, respectively. Early-stage cervical cancer patients with intra-operative detection of pelvic node metastases who underwent complete radical hysterectomy had favorable survival outcomes and manageable complications.