Treatment of reactive stuporous states with L-DOPA
Morozov, G.V.; Lukacher, G.I.; Anokhina, I.P.; Kudriavtsev, I.A.; Morozova, T.G.
Zhurnal Nevropatologii i Psikhiatrii Imeni S.S. Korsakova 78(4): 537-542
1978
ISSN/ISBN: 0044-4588 PMID: 654727 Document Number: 138579
The paper presents the results of L-dopa use for the treatment of patients with reactive stuporous states. The assumption concerning curability of these patients is based on the similarity of a number of their clinical and biochemical manifestations with an akynetic-rigid form of parkinsonism where L-dopa is very effective. From 25 patients with reactive psychoses 7 demonstrated recovery, 3 patients--significant improvement, 5 patients--improvement and 10 patients--absence of the effect. The drug is the most effective in the stuporous depth of psychomotor inhibition in persons with a monomorphic structure of stuporous syndromes, rather "frequent" depressive disorders and a decrease of a background level of dopamine excreation with urine. Use of L-dopa in schizophrenic stuporous states (5 patients) was ineffective.