Nonspecific Biochemical Changes under Different Health Statuses and a Quantitative Model Based on Biological Markers to Evaluate Systemic Function in Humans
Hongwei, W.; Xinyu, Z.; Guihong, L.; Xiliang, L.; Hui, L.
Clinical Laboratory 56(5-6): 223-225
2010
ISSN/ISBN: 1433-6510 PMID: 20575470 Document Number: 13742
Background: To investigate the markers of systemic function by using laboratory parameters as life parameters. Methods: Lymphocyte count, albumin, and creatinine levels were measured using automatic analyzers in young, healthy individuals (20–39 years) and senior individuals (80–95 years) as well as in terminally ill patients. We developed a mathematic model and scoring system (indexes of systemic function, ISF) based on the above mentioned biological markers. Results: ISF scores were significantly lower in the senior group (P Conclusions: Our results suggest that the ISF scoring system of systemic function can be used to objectively evaluate the systemic function in individuals with different health statuses.
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