Somatostatin--paracrine and neuromodulator peptide in gut and nervous system
Pimstone, B.L.; Berelowitz, M.
South African Medical Journal 53(1): 7-9
1978
ISSN/ISBN: 0256-9574 PMID: 25488 Document Number: 136936
Somatostatin, a tetradecapeptide widely distributed in nervous tissue and gut, has inhibitory effects on secretion and neuromuscular activity. The actions of this peptide probably embrace three types of transmitter-receptor interaction, namely that of a neurotransmitter in the nervous system, that of a hormone in the hypophyseal portal circulation and that of a local (paracrine) effector in gut and pancreas.
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