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Effect of short-term antiorthostatic hypokinesia on the central and intracardiac hemodynamics and metabolism in a healthy human being

Katkov, V.E.; Chestukhin, V.V.; Zybin, O.K.; Sukhotskiĭ, S.S.; Abrosimov, S.V.

Kardiologiia 18(12): 69-75

1978

ISSN/ISBN: 0022-9040
PMID: 732085
Document Number: 136169
The right parts of the heart and the radial artery were catheterized in healthy male volunteers before and 5 days after strict bed rest in antiorthostatic position of the body (-4.5 degrees) After immobilization most values of central circulation showed no essential changes; the only exception were indices characterizing the inotropic myocardial condition. A shift in the direction of acidosis of a mixed character was noted in mixed venous blood, the beta-lipoprotein content increased. A decrease in the arteriovenous difference in oxygen was encountered in blood draining from the heart (from the coronary sinus).

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