Management of impending necrosis associated with soft tissue filler injections
Dayan, S.H.; Arkins, J.P.; Mathison, C.C.
Journal of Drugs in Dermatology Jdd 10(9): 1007-1012
2011
ISSN/ISBN: 1545-9616 PMID: 22052269 Document Number: 13464
As the number of soft tissue filler injections increases, the number of adverse events associated with injection may rise. Impending necrosis represents a serious complication that, if not treated correctly and timely, may have grave consequences. We describe a protocol utilizing hyaluronidase, nitroglycerin paste, aspirin, antacid and a topical oxygen therapy that may be used to treat impending necrosis subsequent to injection with soft tissue fillers. We have successfully treated nine post-filler injection adverse events involving impending necrosis or necrosis following both hyaluronic acid and calcium hydroxylapatite injections using our protocol.
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