Levofloxacin-induced severe thrombocytopenia
Polprasert, C.; Prayongratana, K.
Journal of the Medical Association of Thailand 92(Suppl 3): S69-S71
2009
ISSN/ISBN: 0125-2208 PMID: 19702070 Document Number: 13359
Thrombocytopenia following drug administration is commonly found in clinical practice. Recognition of this condition is important for further management of the patients. Many drugs were reported to be the cause of drug induced thrombocytopenia but levofloxacin was rarely reported. We present a seventy-eight-year-old male patient who developed severe thrombocytopenia with hemoptysis after taking levofloxacin for 4 days due to infected bronchiectasis. His platelet count was gradually recovered to normal value after the discontinuation of levofloxacin. Levofloxacin can cause severe thrombocytopenia. Specific antibody to platelet surface glycoproteins caused by levofloxacin should be further studied to confirm the association.