Effect of CO2 on the excitable membrane of a single node of Ranvier
Katalymov, L.L.
Biulleten' Eksperimental'noi Biologii i Meditsiny 86(10): 89-91
1978
ISSN/ISBN: 0365-9615 PMID: 708887 Document Number: 133465
Introduction into the chamber containing the preparation of a gaseous mixture with a 5% CO2 content failed to lead to any significant changes in the recorded parameters of the node of Ranvier. Elevation of CO2 concentration to 50% caused a significant increase of resistance, of the critical level of the membrane depolarization, a decrease of the spike amplitude, and of the maximum steepness of its increase. Two minutes after the beginning of the gas mixture introduction spike degeneration stopped. CO2 action was completely reversible. The trace potentials of the node of Ranvier remained unchanged with the CO2 action in the mentioned concentrations.