Effect of peptichemio upon localization of injected radiolabelled lymphocytes in the lymphatic organs of antigen-stimulated mice
Caruso, C.; Benvegna, S.; Palmeri, P.; Cillari, E.
Tumori 64(1): 25-31
1978
ISSN/ISBN: 0300-8916 PMID: 653829 Document Number: 133203
Increased localization (trapping) of lymphocytes occurs in lymphoid organs following antigenic challenge. The effect of peptichemio (PTC) upon lymphocyte trapping in lymph nodes and spleen was investigated: PTC diminishes trapping in lymphatic organs. The depression of lymphocyte trapping may provide at least 1 mechanism whereby PTC achieves its immunosuppressive effects.
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