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Three levels of structural organization of the eukaryotic chromosomes

Georgiev, G.P.; Bakaev, V.V.

Molekuliarnaia Biologiia 12(6): 1205-1230

1978

ISSN/ISBN: 0026-8984
PMID: 745600
Document Number: 132792
Three levels of structural organization of eukaryotic DNA in the cell nucleus are considered in this paper: (i) the chain of nucleosomes; (ii) the solenoidal or superbead (nucleomere) model of compactization of the nucleosomal fiber; (iii) the mode of suprasolenoidal DNP-packing--loops or domains. Recent results bearing on the relation of these three levels to functional activity of chromatin are also discussed.

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