Myopathy and hypothyroidism
Ramírez Mayans, J.; Salas Alvarado, M.; Coutiño, B.
Boletin Medico del Hospital Infantil de Mexico 35(2): 343-354
1978
ISSN/ISBN: 0539-6115 PMID: 626657 Document Number: 131936
Muscular disturbances in hypothyroid children are: generalized muscular weakness of proximal predominance, muscular hypotonicity, pseudohypertrophy (of gastrocnemius muscles chiefly), slow relaxation stage of osteotendinous reflexes, rise of muscular enzymes (CPK andaldolase), unspecific electromyographic changes and histopathologic disturbances comprised by persistent decrease of fibers type II. All these changes are reversible with thyroglobulin therapy; therefore they exert no influence on the prognosis of hypothyroid patients.