Transbronchial mucus transfer of bronchogenic carcinoma
Cattaneo, S.M.; Zipf, R.E.; Johnson, O.E.; Everhart, L.S.
Journal of Thoracic and Cardiovascular Surgery 75(4): 585-594
1978
ISSN/ISBN: 0022-5223 PMID: 642553 Document Number: 131628
The metastatic transfer of cells from a primary bronchogenic carcinoma to other portions of the lung as a result of mucus embolization and inoculation has been demonstrated. Histologic observations indicate tumor implantation and survival in peripheral bronchioles. In these regions mucosal dysplasia and carcinoma-in-situ changes which characteristically accompany a primary lesion are notably absent. Morphologic changes associated with acute bronchitis and focally denuded bronchial mucosa may be implicated.