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Inhaled corticosteroid-induced hair depigmentation in a child

Bezzina, C.; Bondon-Guitton, E.; Montastruc, J.-L.

Journal of Drugs in Dermatology Jdd 12(1): 119-120

2013

ISSN/ISBN: 1545-9616
PMID: 23377340
Document Number: 13153
An Afro-Caribbean girl showed localized hair depigmentation during treatment with inhaled fluticasone propionate. Although skin depigmentation is common after topical use of corticosteroids, hair depigmentation has never been reported with inhaled corticosteroids. The mechanisms underlying corticosteroid-induced skin depigmentation are not completely understood, but accepted hypotheses suggest a direct cytotoxic effect, changes in ground substance, vasoconstriction, mechanical effects of edema, or a dysregulation of melanogenesis.

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Inhaled corticosteroid-induced hair depigmentation in a child

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