In vitro prostaglandin biosynthesis in human pregnant uterus from arachidonic acid
Falkay, G.; Herczeg, J.; Sas, M.
Acta Biologica et Medica Germanica 37(5-6): 941-943
1978
ISSN/ISBN: 0001-5318 PMID: 742317 Document Number: 131471
Formation of prostaglandins (F2alpha, E2 and D2) in the pregnant human uterus microsomes was studied using 14C-labeled arachidonic acid. Sample of uterine pieces were removed from the lower uterine segment at the time of Caesarean section. The prostaglandin synthesis in the microsomal fraction was characterized in terms of cofactors, substrate concentration and incubation time requirements.
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