Stimulating action of the albumin fraction of soluble placental proteins on T- and B-lymphocyte transformation
Fogel, P.I.
Voprosy Onkologii 24(1): 48-50
1978
ISSN/ISBN: 0507-3758 PMID: 305685 Document Number: 130894
Under study was the effect of the albumin fraction of soluble placental proteins on the transformation of T- and B-lymphocytes, stimulated by Salmonellae phytohemagglutinin and lipopolysaccharides, respectively. Placental proteins were separated by their fractional sedimentation with ammonium sulphate and subsequent gelfiltration on Sephadex-G-200. The albumin fraction of placental proteins was shown to stimulated the reaction of the T- and B-lymphocytes blasttransformation. Some possible mechanisms of this effect are discussed.