Role of B-lymphocytes in inactivating allogenic stem cells
Man'ko, V.M.; Khalat'ian, N.A.; Rudneva, T.B.
Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 11: 81-85
1978
ISSN/ISBN: 0372-9311 PMID: 31752 Document Number: 130228
Antisera to membrane antigens of B lumphocytes eliminated the capacity of lymphocytes to inactivate allogenous stem cells by 60%; however, lymphocytes from the lymph nodes of B mice possessed no inactivating capacity. T-lymphocytes were the main criteria inactivating allogenous stem cells. Cooperating with T-lymphocytes, B-lymphocytes probably contributed to inactivation of precursor cells realized by T-lymphocytes. However, the presence of B-lymphocytes in the killer cells population was not a determinant, since T-lymphocytes were capable of inactivating allogenous stem cells without any participation of B-lymphocytes.