Arginine aspartate effects on acute human alcoholizing test
Elsair, J.; Poey, J.; Denine, R.; Reggabi, M.
Toxicological European Research. Recherche Europeenne en Toxicologie 1(5): 311-315
1978
ISSN/ISBN: 0249-6402 PMID: 552171 Document Number: 128915
One oral arginine aspartate administration (10g), 30 minutes after the beginning of acute human alcoholizing test (150 ml whisky 45 degrees, 67,5 g pure alcohol, mean load about 1 g/kg), provokes the following effects. Clinically, intensity and lasting alcohol manifestations are reduced. Alcoholemic absolute curve (g/l) does not vary: 1 h peak equal in the two treated and non treated groups, similar 6 h levels but a little lesser in the treated subjects, without significative difference. Alcohol space does not vary. Arginine aspartate provokes a significant increase between 1 h and 4 h of alcoholemic disparition slope, when rapported to body weight: mg/kg/h (p < 0,02), and ethyloxydation coefficient: mg/kg/h (p < 0,05).