A mutation affecting the sigma subunit of RNA polymerase changes transcriptional specificity
Travers, A.A.; Buckland, R.; Goman, M.; Le Grice, S.S.; Scaife, J.G.
Nature 273(5661): 354-358
1978
ISSN/ISBN: 0028-0836 PMID: 351406 Document Number: 124601
The [Escherichia coli] RNA polymerase mutation, alt-1, affects the .sigma. subunit and alters the in vitro selectivity of RNA polymerase to parallel the in vivo phenotype. The mutation apparently changes the distribution of functionally distinct polymerase isomers.
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