Histo-autoradiographic study of a testosterone target organ, the epididymis of the lizard (Lacerta vivipara) , after administration of 3H-17 beta-estradiol
Dufaure, J.P.; Chambon, M.
Comptes Rendus des Seances de la Societe de Biologie et de ses Filiales 172(6): 1127-1130
1978
ISSN/ISBN: 0037-9026 PMID: 159099 Document Number: 124400
[6,7 3H] oestradiol-17 beta was injected into castrated male viviparous lizards in order to compare retention of this steroid to that of testosterone during the period of sexual activity. Retention of the isotope in epididymis was greater than in blood, lung and stomach. Radioautographs of epididymis indicated that oestradiol or a metabolite was concentrated in cell nuclei and over discharged secretory granules as was observed with testosterone. Reason of such binding is not yet known.