Ultrastructure of the red pulp of the spleen in various thrombocytopenias
Jakubovský, J.; Ondrus, B.; Svitok, I.; Zaviacic, M.; Lipsic, T.; Hutan, L.; Schnorer, M.
Ceskoslovenska Patologie 13(3): 108-112
1977
ISSN/ISBN: 1210-7875 PMID: 567536 Document Number: 123326
The authors describe 10 cases of samples of spleen tissue obtained from patients with various thrombocytopenias which had been subjected to electron microscopical examinations. In splenomegalies associated with liver cirrhoses a certain proportion of platelets accumulated in the spleen, whereas others were ingested by macrophages. No significant polymorhism of the platelets was observed. In cases of idiopathic thrombocytopenic purpura marked polymorphism of the platelets as regards size and structure was observed. The platelets also showed a concoisuous relation to the polymorphonuclear laucotytes. The alterations of the inner structure of the platelets could not be regarded as specific, because they were also found in lymhogranuloma.