Subjective phenomena in drug trials
Gagnon, M.A.
International Journal of Clinical Pharmacology and Biopharmacy 15(4): 155-160
1977
ISSN/ISBN: 0340-0026 PMID: 323162 Document Number: 122716
Three types of problem arise from subjective phenomena in drug trials: problems of control, measurement, and analysis. Examples are given in order to illustrate these three aspects and to present some recent advances in clinical pharmacology. The author discusses the control of drug compliance, the validity of questionnaires, the subjectivity of the observer and that of the observations. Drug side-effects and the statistical analysis of qualitative data are presented in more detail.