Error in anti-DNA antibody radioimmunoassay after gallium scanning
Torretti, D.; Rooney, P.; Williams, G.; Decker, J.L.
Annals of Internal Medicine 86(3): 309-311
1977
ISSN/ISBN: 0003-4819 PMID: 300227 Document Number: 122093
Significant interference with the accurate measurement of anti-DNA antibodies occurs after gallium-67 scanning. The observed effect is dependent on the radioimmunoassay used. False-negative results are observed with a modified Farr assay whereas false-positive results are noted in the millipore filter assay. These spurious values are the result of persistent radioactivity in the patients' sera after administration of 67Ga citrate.