Digoxin and congestive heart failure
Fantini, F.; Lucchini, C.R.; Padeletti, L.; Marsilii, A.; Dolara, P.; Mannelli, M.
Acta Cardiologica 32(5): 353-362
1977
ISSN/ISBN: 0001-5385 PMID: 304654 Document Number: 121453
The purpose of our study was to evaluate the absorption of digoxin in alcoholic solution in normal subjects and in patients on congestive heart failure whose water and electrolyte balances were determined. While the parameters of the distribution kinetics were not significantly different between the two groups, the areas under the serum concentration curve resulted increased in the patients on congestive heart failure indicating a more efficient absorption respect to the normal subjects.