Centrifugal analysis. History, general principles
Bretaudiere, J.P.
Annales de Biologie Clinique 35(3): 157-166
1977
ISSN/ISBN: 0003-3898 PMID: 900596 Document Number: 120803
Three ideas were at the origin of the concept of rapid centrifugal analysis: automation, miniaturisation, suppleness. They led to the drawing up of a manuel for the development of a prototype including: simultaneity, miniaturisation, true time and reduction of data. The rapid centrifugal analyser may be described as a system of analysis based on the use of centrifugal force to add simultaneously in a discret way an aliquot of reagent to various aliquots of specimens and to displace the reactional mixtures in hollows equally distributed on the outer border of a rotor. The signals are detected optically. After showing the various forms of use of the rotors, the function of the module of analysis is described. The taking and treatment of data by the computer are described with special reference to their aspects in real time. Finally, a few applications are described.