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Urinary excretion of individual 17-ketosteroids in intact male dogs and rabbits

Bondarenko, L.A.

Fiziolohichnyi Zhurnal 23(3): 400-402

1977

ISSN/ISBN: 0015-3311
PMID: 872982
Document Number: 120378
Optimal conditions for assaying individual 17-ketosteroids (17-KS) and 17-KS fractional composition in rabbits and dogs by TLC are described for possible comparative evaluation of the effect of prostate gland dysfunction on androgenic activity. Insignificant quantities of 17-KS, 11-hydroxycorticosterone, etiocholanolone, androsterone and dehydroepiandrosterone were excreted. Of the total androgens excreted, 38-41% were testosterone metabolites. The animal species selected are suitable for studying endocrine disorders or other diseases related to steroidogenic dysfunction.

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