Onset of illness in bipolar manic-depressives and their affectively ill first-degree relatives
Johnson, G.F.; Leeman, M.M.
Biological Psychiatry 12(6): 733-741
1977
ISSN/ISBN: 0006-3223 PMID: 597526 Document Number: 119161
Some suggestive data regarding age of onset and the relationship of stress to onset in a group of bipolar manic-depressive patients and their first-degree relatives are presented. Possible explanations of the interesting correlation in age of onset among family members are discussed. Because of a small sample size, the clinical significance of the findings are uncertain, but are presented because of their potential interest to those investigating genetic components of affective illness.