An immunoglobulin heavy chain variable region (VH) marker associated with cross-reactive idiotypes in man
Feizi, T.; Lecomte, J.; Childs, R.
Clinical and Experimental Immunology 30(2): 233-241
1977
ISSN/ISBN: 0009-9104 PMID: 414866 Document Number: 117382
The VH specificities of 2 rabbit antisera raised against the H chains of 2 human Ig antibodies which have cross-reactive idiotypes. It is moderately well-expressed in normal .gamma.-globulin and strongly expressed on 8% of unselected myeloma and macroglobulinemia proteins. There is evidence to sugest that a proportion of the cross-reactive idiotypes among the anti-Ii antibodies involve this VH antigen.
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