Desamino arginine vasopressin (DDAVP) as a diagnostic agent

Somerfield, S.D.; Hocken, A.G.

New Zealand Medical Journal 86(600): 472-473

1977


ISSN/ISBN: 0028-8446
PMID: 343010
Document Number: 117099
The use of 1-desamino-8-arginine vasopressin (DDAVP) was examined as a diagnostic agent, within the context of the comprehensive one day renal function test. Thirty-three normal young subjects were examined in an 8 1/2 hour day. It was found that a 20 microgram intranasal dose of DDAVP consistently resulted in the production of a urinary osmolality to 800mosmol/kg or more, with no untoward effect. DDAVP can advantageously replace pitressin tannate in oil as a diagnostic agent.

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