Comparison of Serum Specific IgE and Skin Prick Test in Polysensitized Children
Ciprandi, G.; Amici, M.D.; Marseglia, G.
Clinical Laboratory 57(1-2): 83-85
2011
ISSN/ISBN: 1433-6510 PMID: 21391469 Document Number: 11708
Background: Skin prick test (SPT) and serum specific IgE (ssIgE) measurements are the most common methods used to diagnose allergy. The aim of this study was to evaluate serum specific-IgE in a large group of polysensitized patients with the same SPT result (such as ++++) comparing the two diagnostic methods. Methods: Four hundred ninety-four children (310 males; median age 10 years) suffering from allergic rhinitis were studied. Serum specific-IgE values were measured by ImmunoCap assay. Skin prick test was also performed. Results: There was a significant difference (p Conclusions: The ss-IgE measurements in polysensitized patients seem to be more appropriate than SPT.
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