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Content of free amino acids in rabbit tissues as affected by adrenalectomy and administration of hydrocortisone and ACTH

Mishunina, T.M.; Mestechkina, A.I.; Lisak, V.F.

Ukrains'kyi Biokhimichnyi Zhurnal 49(6): 12-18

1977

ISSN/ISBN: 0041-610X
PMID: 201065
Document Number: 116670
Adrenalectomy is accompanied by a decreased content of free amino acids in muscules and blood plasma by an increased content of certain amino acids in the liver. A single injection of hydrocortisone to adrenalectomized animals increases the content of amino acids in muscles and lowers their total content in the liver; a single injection of ACTH lowers the total content of amino acids in the liver and blood plasma "Substitutive therapy" by hydrocortisone essentially increases the content of amino acids in the liver, muscles and blood plasma. Under conditions of the experiment the least changes in the content of amino acids were found in the brain tissue.

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