Nucleo-cytoplasm ratio, DNA content of superficial and intermediate vaginal cells during the female genital cycle

Laurent, J.L.; Gout, C.; Chappard, D.; Pasteur, X.; Souchier, C.; Laurent, J.L; Gout, C; Chappard, D; Pasteur, X; Souchier, C

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Nucleo-cytoplasm ratio, DNA content of superficial and intermediate vaginal cells during the female genital cycle

Laurent, J.L.; Gout, C.; Chappard, D.; Pasteur, X.; Souchier, C.

Bulletin de l'Association des Anatomistes 61(174): 357-367

1977

ISSN/ISBN: 0376-6160

PMID: 614073

Document Number: 115239

A quantimetric study of vaginal superficial cells is done every day of the sexual cycle on five normal women (no pill) with a cervical smear of type 2 (Papanicolaou classification). Our results show that nucelo-cytoplasmic ratio for 98% of the cells varies between 0.0040 and 0.0210. This level is independant of age and cycle duration and is proposed as reference for later studies of women under pill or with cervico-vaginal dysplasia and cancer.