Clinical profiles of Thai patients with ocular myasthenia gravis in Siriraj Hospital
Leeamornsiri, S.; Chirapapaisan, N.; Chuenkongkaew, W.
Journal of the Medical Association of Thailand 94(9): 1117-1121
2011
ISSN/ISBN: 0125-2208 PMID: 21970202 Document Number: 11516
Ninety-six patients with ocular myasthenia gravis (OMG) seen at Siriraj Hospital during 1994 to 2004 were retrospectively reviewed. There were 59 female (61.5%) and 37 (38.5%) male patients with mean ages of 39.5 and 33.8 years, respectively Patients presented with initial symptoms of only ptosis in 46.9%, only diplopia in 13.5% and both ptosis and diplopia in 39.6%. However, diplopia alone is uncommon in childhood OMG. Fifteen percent developed systemic symptoms within two years of diagnosis. Thyroid function test was abnormal in 27.5% of investigated patients. Most abnormalities were hyperthyroidism. Thymoma associated with OMG is a rare condition. Most purely OMG patients can control the disease by pyridostigmine, prednisolone or immunosuppressive drugs.
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