Effect of analytical factors on immunochemical reference limits for complement component C3 in serum of a reference pediatric population
Buffone, G.J.; Lewis, S.A.
Clinical Chemistry 23(6): 994-999
1977
ISSN/ISBN: 0009-9147 PMID: 404096 Document Number: 114953
We evaluated analytical factors such as antibody specificity, standard materials, and methodology for the measurement of C3. Mancini-type radial immunodiffusion and immunonephelometry were shown to give comparable data if variables other than procedural variables are eliminated. The most significant analytical factors affecting the measurement were antiserum specificity and source of standard material.